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Vonoref-20 Tablet



Vonoprazan Tablets 20 mg - Manufacturers & Suppliers - Third Party Contract Manufacturing

Vonoref-20 Tablet

Product Name : Vonoref-20 Tablet

Composition : Vonoprazan Tablets 20 mg

Packing : 10×10 Alu-Alu

Price : Rs.

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Vonoprazan Tablets 20 mg sold under the brand name Vonoref 20 tablet are a first-in-class potassium-competitive acid blocker (PCAB) used to treat acid-related gastrointestinal disorders, including erosive esophagitis, gastroesophageal reflux disease (GERD), and Helicobacter pylori infections when combined with antibiotics like amoxicillin and clarithromycin. It rapidly and reversibly inhibits gastric acid secretion by competing with potassium at the proton pump, offering faster and more sustained acid suppression.

These tablets are manufactured by the ISO and GMP-certified company Biophar Life Sciences, which is a great Vonoprazan tablets manufacturer and supplies them worldwide. Biophar Life Sciences also offers great career opportunities for various young entrepreneurs who want to start their careers in the healthcare profession with support and guidance.

Working Mechanism of Vonoprazan Tablets 20 mg (Vonoref 20)

Vonoprazan is a potassium-competitive acid blocker (PCAB) that works by rapidly and reversibly inhibiting the H+/K+-ATPase (proton pump) in gastric parietal cells, thereby reducing stomach acid production. Vonoprazan blocks acid secretion directly and potently, providing faster and longer-lasting suppression of gastric acid.
This mechanism helps in treating acid-related disorders like GERD, peptic ulcers, and H. pylori infections by maintaining a higher gastric pH, promoting healing, and relieving symptoms such as heartburn and indigestion. Its strong acid-suppressing effect makes it particularly effective for conditions requiring sustained pH control.

Key Indications of Vonoprazan 20 mg Tablets | Vonoref 20 Tablet

Vonoprazan tablets are a potassium-competitive acid blocker (PCAB) used to reduce stomach acid production. It provides fast and long-lasting relief from acid-related disorders by inhibiting gastric H+/K+-ATPase enzymes effectively.

Key Indications:

  • Gastroesophageal Reflux Disease (GERD) – Treats heartburn and acid reflux by reducing stomach acid, allowing esophageal healing.
  • Peptic Ulcers (Gastric & Duodenal) – Promotes ulcer healing by decreasing acid secretion in the stomach.
  • Helicobacter pylori (H. pylori) Eradication – Used in combination with antibiotics to eliminate infection and prevent ulcer recurrence.
  • Gastric Hypersecretory Conditions (e.g., Zollinger-Ellison Syndrome) – Controls excessive acid production in rare hypersecretory disorders.

Vonoprazan works faster and more potently than traditional PPIs, maintaining a higher pH in the stomach for prolonged periods, ensuring better symptom relief and mucosal healing.

PCD Pharma Franchise Opportunities for Vonoprazan Tablets 20 mg

If you're looking for lucrative PCD pharma franchise opportunities for Vonoprazan Tablets, Biophar Life Sciences is a trusted name in the industry, offering high-quality products with excellent profit margins. Biophar Life Sciences is a trust Vonoprazan 20 mg tablet manufacturer that provides comprehensive franchise support, including monopoly rights, attractive pricing, promotional materials, and hassle-free logistics, making it an ideal partner for aspiring pharma entrepreneurs. With a commitment to GMP-certified manufacturing and ethical business practices, partnering with Biophar Life Sciences ensures a profitable and sustainable franchise venture in the growing gastroenterology segment.
Key Highlights:

  • Exclusive franchise rights are available for dedicated business partners.
  • High-demand product for GERD and acid-related disorders treatment.
  • GMP-certified manufacturing ensures top-quality formulations.
  • Attractive profit margins with flexible business terms.
  • Comprehensive marketing and promotional support provided.
  • Monopoly rights offered for selected territories.
  • Easy documentation and a hassle-free onboarding process.
  • Strong logistics network for pan-India distribution.
  • Doctor-approved formulations with proven efficacy.
  • Customizable packaging options are available.

Dosage Instructions for Vonoprazan 20 mg Tablets 

Take the tablet exactly as prescribed by your doctor, swallowing it whole with water—do not crush, chew, or break it. The tablet can be taken with or without food, but maintaining a consistent routine (either always with meals or always on an empty stomach) is recommended for optimal absorption. 

For best results, take it at the same time each day. Do not exceed the prescribed dosage, and consult your doctor before making any changes to your treatment plan. If you miss a dose, take it as soon as you remember, unless it's close to the next scheduled dose; in that case, skip the missed dose to avoid doubling up.

Storage Instructions for Vonoprazan Tablets 20 mg | Vonoref 20 Tablet

Vonoprazan tablets should be stored at room temperature in a cool, dry place, away from direct sunlight, moisture, and extreme cold (freezing conditions). To maintain the medicine's effectiveness, ensure the container is tightly closed. Additionally, keep it out of reach of children and pets to prevent accidental ingestion. Proper storage helps preserve the tablet's stability and potency.

Superior Quality and Innovative Packaging for Vonoprazan Tablets

Biophar Life Sciences is a well-renowned Vonoprazan 20mg tablets manufacturer who prioritizes uncompromised quality and advanced packaging for Vonoprazan Tablets, ensuring maximum efficacy and patient satisfaction. Manufactured in GMP-certified facilities, each batch undergoes strict quality control to guarantee high potency, stability, and fast-acting relief from acid-related disorders. With patient-friendly designs and brand-centric packaging, we help franchise partners build trust and boost recall value in a competitive market.

Key Features:

  • GMP & ISO-Certified Manufacturing – Assures pharmaceutical-grade quality
  • Third-Party Lab Tested – For purity, dissolution, and bioavailability
  • Advanced Blister Packaging – Tamper-proof, moisture-resistant, and travel-friendly
  • Custom Branding Options – Enhance brand visibility and market appeal
  • Eco-Conscious Materials – Sustainable yet compliant packaging solutions

Precautions for Using Vonoprazan 20 mg Tablets | Vonoref 20 Tablet

The safety measures for using Vonoprazan tablets 20 mg are:

  • Consult a doctor before use if you have kidney or liver issues.
  • Avoid if allergic to vonoprazan or its components.
  • Monitor for low magnesium levels during long-term use.
  • Do not combine with rilpivirine or other contraindicated drugs.
  • Inform your doctor about all medications to avoid interactions.
  • Use cautiously in pregnancy or breastfeeding; consult a physician.
  • Watch for signs of serious side effects like severe diarrhea.
  • Avoid long-term use without medical supervision due to polyp risk.
  • Not recommended for children; safety data is limited.
  • Report any unusual symptoms, such as kidney problems, immediately.

Side Effects of Having Vonoprazan Tablets 20 mg

The side effects of consuming Vonoprazan tablets 2 mg are given below:

  • Nausea or vomiting
  • Stomach pain or discomfort
  • Diarrhea or constipation
  • Gas or bloating
  • Headache
  • Dizziness
  • Dry mouth
  • Loss of appetite
  • Rash or itching 

Why Vonoref 20 is the Next-Gen Solution for Acid-Related Disorders

In a market dominated by conventional Proton Pump Inhibitors (PPIs), Vonoref 20 by Biophar Life Sciences introduces a breakthrough approach to managing acid-related gastrointestinal issues. As a Potassium-Competitive Acid Blocker (PCAB), Vonoref 20 delivers faster onset, greater acid suppression, and more consistent pH control, making it a preferred choice for both doctors and patients.

Vonoref 20 vs Traditional PPIs:

Feature Vonoref 20 (Vonoprazan) Traditional PPIs (e.g., Omeprazole)
Onset of Action Within 1–2 hours 24–72 hours
Reversibility Reversible inhibition Irreversible
Acid Suppression Duration 24+ hours Variable
Food Dependency Not food-dependent Should be taken before meals
Drug Stability in Acidic pH High Lower

Advantages of Partnering with Biophar Life Sciences for Vonoprazan 20 mg Tablets

Biophar Life Sciences stands out not only for quality but also for its entrepreneur-first pharma franchise ecosystem. Here's why more partners across India and international markets are choosing us:

Dedicated Relationship Managers for franchise partners
Timely stock delivery and real-time inventory tracking
Quick reordering system via mobile or web
R&D-backed product innovations for future-ready business
Regulatory-compliant exports for international pharma trade

Who Should Consider Taking Vonoprazan Tablets 20 mg?

Vonoref 20 is ideal for individuals suffering from moderate to severe acid-related issues who are not responding well to PPIs. Typical candidates include:

  • Chronic GERD patients with nighttime symptoms
  • Individuals with NSAID-induced ulcers
  • Patients needing dual or triple therapy for H. pylori
  • People experiencing rebound acid hypersecretion on stopping PPIs

Always consult a gastroenterologist before switching to Vonoprazan therapy.

Market Outlook: Rising Demand for PCABs Like Vonoprazan

The global PCAB market is projected to grow at a CAGR of over 8%, with India becoming a significant contributor due to increasing cases of GERD, peptic ulcers, and H. pylori infections. This makes Vonoprazan PCD franchises a high-growth opportunity.

Biophar Life Sciences is strategically positioned to meet this rising demand with robust infrastructure, skilled pharma professionals, and a proactive supply chain model.


Frequently Asked Questions (FAQs)

How long does a Vonoprazan 20 mg tablet - Vonoref 20 take to work?

Starts reducing acid within 1-2 hours, with full effect in 2-3 days.

Can Vonoprazan tablets 20 mg be taken long-term?

Generally safe for short-term use (4-8 weeks for GERD). Long-term use may require monitoring for side effects (e.g., bone fractures, low magnesium).

Can Vonoprazan 20 mg tablets be taken with other medicines?

May interact with HIV drugs (atazanavir, rilpivirine), blood thinners (warfarin), and some antifungals. Consult a doctor before combining medications.

Do Vonoprazan tablets 20 mg cause vitamin deficiencies?

Long-term use may reduce Vitamin B12, magnesium, or iron absorption due to low stomach acid.

What if I miss a dose?

Take it as soon as you remember, but skip if close to the next dose